Cargando…

Cytotoxicity of Isoxazole Curcumin Analogs on Chronic Myeloid Leukemia-Derived K562 Cell Lines Sensitive and Resistant to Imatinib

Despite curcumin (CUR) inhibiting cell proliferation in vitro by activating apoptotic cell death, its use in pharmacological therapy is hampered by poor solubility, low stability in biological fluids, and rapid removal from the body. Therefore, CUR-derivatives with better biological and chemical–phy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feriotto, Giordana, Marchetti, Paolo, Rondanin, Riccardo, Tagliati, Federico, Aguzzi, Serena, Beninati, Simone, Casciano, Fabio, Tabolacci, Claudio, Mischiati, Carlo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916957/ https://www.ncbi.nlm.nih.gov/pubmed/36768681 http://dx.doi.org/10.3390/ijms24032356

Ejemplares similares

Characterization of Stable Pyrazole Derivatives of Curcumin with Improved Cytotoxicity on Osteosarcoma Cell Lines
por: Feriotto, Giordana, et al.
Publicado: (2023)

Caffeic Acid Enhances the Anti-Leukemic Effect of Imatinib on Chronic Myeloid Leukemia Cells and Triggers Apoptosis in Cells Sensitive and Resistant to Imatinib
por: Feriotto, Giordana, et al.
Publicado: (2021)

A Central Contribution of TG2 Activity to the Antiproliferative and Pro-Apoptotic Effects of Caffeic Acid in K562 Cells of Human Chronic Myeloid Leukemia
por: Feriotto, Giordana, et al.
Publicado: (2022)

The Role of Tissue Transglutaminase in Cancer Cell Initiation, Survival and Progression
por: Tabolacci, Claudio, et al.
Publicado: (2019)

Flavonoids: A Myth or a Reality for Cancer Therapy?
por: Forni, Cinzia, et al.
Publicado: (2021)

Polyamine Oxidase Is Involved in Spermidine Reduction of Transglutaminase Type 2-Catalyzed βH-Crystallins Polymerization in Calcium-Induced Experimental Cataract
por: Mischiati, Carlo, et al.
Publicado: (2020)

Reduction in Fatigue Symptoms Following the Administration of Nutritional Supplements in Patients with Multiple Sclerosis
por: Ferorelli, Pasquale, et al.
Publicado: (2021)

Proteome Changes Induced by Imatinib and Novel Imatinib Derivatives in K562 Human Chronic Myeloid Leukemia Cells
por: Arvaniti, Katerina, et al.
Publicado: (2014)

Cytotoxic Effects of Some Flavonoids and Imatinib on the K562 Chronic Myeloid Leukemia Cell Line: Data Analysis Using the Combination Index Method
por: Danışman Kalındemirtaş, Ferdane, et al.
Publicado: (2019)

The synthetic and therapeutic expedition of isoxazole and its analogs
por: Agrawal, Neetu, et al.
Publicado: (2018)

Synergistic cytotoxicity effect of the combination of chitosan nanoencapsulated imatinib mesylate and quercetin in BCR-ABL positive K562 cells
por: Kamyabi, Rohollah, et al.
Publicado: (2023)

Curcumin Decreases Viability and Inhibits Proliferation of Imatinib-Sensitive and Imatinib-Resistant Chronic Myeloid Leukemia Cell Lines
por: Bilajac, Esma, et al.
Publicado: (2022)

Time-series analysis in imatinib-resistant chronic myeloid leukemia K562-cells under different drug treatments
por: Zhao, Yan-hong, et al.
Publicado: (2017)

Effect of curcumin analogs onα-synuclein aggregation and cytotoxicity
por: Jha, Narendra Nath, et al.
Publicado: (2016)

Celecoxib suppresses autophagy and enhances cytotoxicity of imatinib in imatinib-resistant chronic myeloid leukemia cells
por: Lu, Ying, et al.
Publicado: (2016)

Targeting Melanoma-Initiating Cells by Caffeine: In Silico and In Vitro Approaches
por: Tabolacci, Claudio, et al.
Publicado: (2021)

Aclacinomycin A Sensitizes K562 Chronic Myeloid Leukemia Cells to Imatinib through p38MAPK-Mediated Erythroid Differentiation
por: Lee, Yueh-Lun, et al.
Publicado: (2013)

Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells
por: Prado-Carrillo, Omar, et al.
Publicado: (2022)

Correction: Aclacinomycin A Sensitizes K562 Chronic Myeloid Leukemia Cells to Imatinib through p38MAPK-Mediated Erythroid Differentiation
por: Lee, Yueh-Lun, et al.
Publicado: (2017)

Pro-apoptotic activity of novel synthetic isoxazole derivatives exhibiting inhibitory activity against tumor cell growth in vitro
por: Lampronti, Ilaria, et al.
Publicado: (2020)

Cytotoxic effect of sea anemone pore-forming toxin on K562 chronic myeloid leukemia cells
por: Abdoli, Vali, et al.
Publicado: (2021)

Apoptosis and autophagy have opposite roles on imatinib-induced K562 leukemia cell senescence
por: Drullion, C, et al.
Publicado: (2012)

New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
por: Oliveira, Andressa, et al.
Publicado: (2022)

Curcumin and Curcumin-Loaded Nanogel Induce Apoptosis Activity in K562 Chronic Myelogenous Leukemia Cells
por: Khatamsaz, Sepideh, et al.
Publicado: (2018)

Editorial: Cancer stem cell differentiation: A realistic potential therapeutic option?
por: Buccarelli, Mariachiara, et al.
Publicado: (2023)

Synthesis and Cytotoxic Evaluation of Monocarbonyl Analogs of Curcumin as Potential Anti‐Tumor Agents
por: Pan, Zheer, et al.
Publicado: (2016)

Semi-random mutagenesis profile of BCR-ABL during imatinib resistance acquirement in K562 cells
por: Dong, Yan, et al.
Publicado: (2017)

The Effects of Antisense miRNA-20a Alone or in Combination with Imatinib on K562 Cell Proliferation
por: Zhou, Ying, et al.
Publicado: (2017)

Artesunate enhances adriamycin cytotoxicity by inhibiting glycolysis in adriamycin-resistant chronic myeloid leukemia K562/ADR cells
por: Chen, Li, et al.
Publicado: (2019)

The In Vitro Impact of Isoxazole Derivatives on Pathogenic Biofilm and Cytotoxicity of Fibroblast Cell Line
por: Bąchor, Urszula, et al.
Publicado: (2023)

The effects of cannabidiol via TRPV2 channel in chronic myeloid leukemia cells and its combination with imatinib
por: Maggi, Federica, et al.
Publicado: (2022)

Alternative splicing of apoptosis-related genes in imatinib-treated K562 cells identified by exon array analysis
por: LIU, JING, et al.
Publicado: (2011)

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells
por: Chen, Shu-Huey, et al.
Publicado: (2019)

Phytochemicals as Immunomodulatory Agents in Melanoma
por: Tabolacci, Claudio, et al.
Publicado: (2023)

Upstream stimulatory factors are involved in the P1 promoter directed transcription of the AbetaH-J-J locus
por: Finotti, Alessia, et al.
Publicado: (2008)

Imatinib in Chronic Myeloid Leukemia: an Overview
por: Sacha, Tomasz
Publicado: (2014)

KPT-330 inhibition of chromosome region maintenance 1 is cytotoxic and sensitizes chronic myeloid leukemia to Imatinib
por: Nie, Danian, et al.
Publicado: (2018)

Calcium influx, oxidative stress, and apoptosis induced by TRPV1 in chronic myeloid leukemia cells: Synergistic effects with imatinib
por: Maggi, Federica, et al.
Publicado: (2023)

Wogonin induces cell cycle arrest and erythroid differentiation in imatinib-resistant K562 cells and primary CML cells
por: Yang, Hao, et al.
Publicado: (2014)

(Phenylamino)pyrimidine-1,2,3-triazole derivatives as analogs of imatinib: searching for novel compounds against chronic myeloid leukemia
por: Pimentel, Luiz Claudio Ferreira, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b7pobdplfpthq1kapn3dc7dp51