Novel Organoruthenium(II) Complex C1 Selectively Inhibits Butyrylcholinesterase without Side Effects on Neuromuscular Transmission

Enzyme butyrylcholinesterase (BChE) shows increased activity in some brain regions after progression of Alzheimer’s disease and is therefore one of the therapeutic targets for symptomatic treatment of this neurodegenerative disorder. The organoruthenium(II) complex [(η(6)-p-cymene)Ru(II)(1-hydroxy-3...

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Detalles Bibliográficos
Autores principales: Trobec, Tomaž, Žužek, Monika C., Sepčić, Kristina, Kladnik, Jerneja, Turel, Iztok, Frangež, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916964/
https://www.ncbi.nlm.nih.gov/pubmed/36769002
http://dx.doi.org/10.3390/ijms24032681

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916964/
https://www.ncbi.nlm.nih.gov/pubmed/36769002
http://dx.doi.org/10.3390/ijms24032681

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