Overexpression of Insulin Receptor Substrate 1 (IRS1) Relates to Poor Prognosis and Promotes Proliferation, Stemness, Migration, and Oxidative Stress Resistance in Cholangiocarcinoma

Cholangiocarcinoma (CCA) is one of the oxidative stress-driven carcinogenesis through chronic inflammation. Insulin receptor substrate 1 (IRS1), an adaptor protein of insulin signaling pathways, is associated with the progression of many inflammation-related cancers. This study hypothesized that oxi...

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Detalles Bibliográficos
Autores principales: Kaewlert, Waleeporn, Sakonsinsiri, Chadamas, Lert-itthiporn, Worachart, Ungarreevittaya, Piti, Pairojkul, Chawalit, Pinlaor, Somchai, Murata, Mariko, Thanan, Raynoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916965/
https://www.ncbi.nlm.nih.gov/pubmed/36768755
http://dx.doi.org/10.3390/ijms24032428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916965/
https://www.ncbi.nlm.nih.gov/pubmed/36768755
http://dx.doi.org/10.3390/ijms24032428

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