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Enantioselective Human Serum Albumin Binding of Apremilast: Liquid Chromatographic, Fluorescence and Molecular Docking Study

The interaction between human serum albumin (HSA) and apremilast (APR), a novel antipsoriatic drug, was characterized by multimodal analytical techniques including high-performance liquid chromatography (HPLC), fluorescence spectroscopy and molecular docking for the first time. Using an HSA chiral s...

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Detalles Bibliográficos
Autores principales: Dombi, Gergely, Horváth, Péter, Fiser, Béla, Mirzahosseini, Arash, Dobó, Máté, Szabó, Zoltán-István, Tóth, Gergő
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916978/
https://www.ncbi.nlm.nih.gov/pubmed/36768492
http://dx.doi.org/10.3390/ijms24032168