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Collagen hydrogel viscoelasticity regulates MSC chondrogenesis in a ROCK-dependent manner

Mesenchymal stem cell (MSC) chondrogenesis in three-dimensional (3D) culture involves dynamic changes in cytoskeleton architecture during mesenchymal condensation before morphogenesis. However, the mechanism linking dynamic mechanical properties of matrix to cytoskeletal changes during chondrogenesi...

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Detalles Bibliográficos
Autores principales: Huang, Danyang, Li, Yuehong, Ma, Zihan, Lin, Hai, Zhu, Xiangdong, Xiao, Yun, Zhang, Xingdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9916999/
https://www.ncbi.nlm.nih.gov/pubmed/36763657
http://dx.doi.org/10.1126/sciadv.ade9497