Myelin Basic Protein Fragmentation by Engineered Human Proteasomes with Different Catalytic Phenotypes Revealed Direct Peptide Ligands of MS-Associated and Protective HLA Class I Molecules

Proteasomes exist in mammalian cells in multiple combinatorial variants due to the diverse regulatory particles and exchange of catalytic subunits. Here, using biotin carboxyl carrier domain of transcarboxylase from Propionibacterium shermanii fused with different proteasome subunits of catalytic an...

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Detalles Bibliográficos
Autores principales: Saratov, George A., Vladimirov, Vasiliy I., Novoselov, Alexey L., Ziganshin, Rustam H., Chen, Guo, Baymukhametov, Timur N., Konevega, Andrey L., Belogurov, Alexey A., Kudriaeva, Anna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917034/
https://www.ncbi.nlm.nih.gov/pubmed/36768413
http://dx.doi.org/10.3390/ijms24032091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917034/
https://www.ncbi.nlm.nih.gov/pubmed/36768413
http://dx.doi.org/10.3390/ijms24032091

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