Finerenone, a Non-Steroidal Mineralocorticoid Receptor Antagonist, Reduces Vascular Injury and Increases Regulatory T-Cells: Studies in Rodents with Diabetic and Neovascular Retinopathy

Vision loss in diabetic retinopathy features damage to the blood–retinal barrier and neovascularization, with hypertension and the renin–angiotensin system (RAS) having causal roles. We evaluated if finerenone, a non-steroidal mineralocorticoid receptor (MR) antagonist, reduced vascular pathology an...

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Detalles Bibliográficos
Autores principales: Jerome, Jack R., Deliyanti, Devy, Suphapimol, Varaporn, Kolkhof, Peter, Wilkinson-Berka, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917037/
https://www.ncbi.nlm.nih.gov/pubmed/36768656
http://dx.doi.org/10.3390/ijms24032334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917037/
https://www.ncbi.nlm.nih.gov/pubmed/36768656
http://dx.doi.org/10.3390/ijms24032334

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