The Mycotoxin Patulin Inhibits the Mitochondrial Carnitine/Acylcarnitine Carrier (SLC25A20) by Interaction with Cys136 Implications for Human Health

The effect of mycotoxin patulin (4-hydroxy-4H-furo [3,2c] pyran-2 [6H] -one) on the mitochondrial carnitine/acylcarnitine carrier (CAC, SLC25A20) was investigated. Transport function was measured as [(3)H]-carnitine(ex)/carnitine(in) antiport in proteoliposomes reconstituted with the native protein...

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Detalles Bibliográficos
Autores principales: Giangregorio, Nicola, Tonazzi, Annamaria, Calvano, Cosima Damiana, Pierri, Ciro Leonardo, Incampo, Giovanna, Cataldi, Tommaso R. I., Indiveri, Cesare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917099/
https://www.ncbi.nlm.nih.gov/pubmed/36768549
http://dx.doi.org/10.3390/ijms24032228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917099/
https://www.ncbi.nlm.nih.gov/pubmed/36768549
http://dx.doi.org/10.3390/ijms24032228

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