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Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson’s Disease

Neuroinflammation and oxidative stress have been emerging as important pathways contributing to Parkinson’s disease (PD) pathogenesis. In PD brains, the activated microglia release inflammatory factors such as interleukin (IL)-β, IL-6, tumor necrosis factor (TNF)-α, and nitric oxide (NO), which incr...

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Detalles Bibliográficos
Autores principales: Chiu, Ya-Jen, Lin, Chih-Hsin, Lin, Chung-Yin, Yang, Pei-Ning, Lo, Yen-Shi, Chen, Yu-Chieh, Chen, Chiung-Mei, Wu, Yih-Ru, Yao, Ching-Fa, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917106/
https://www.ncbi.nlm.nih.gov/pubmed/36768965
http://dx.doi.org/10.3390/ijms24032642