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Investigating Therapeutic Effects of Indole Derivatives Targeting Inflammation and Oxidative Stress in Neurotoxin-Induced Cell and Mouse Models of Parkinson’s Disease
Neuroinflammation and oxidative stress have been emerging as important pathways contributing to Parkinson’s disease (PD) pathogenesis. In PD brains, the activated microglia release inflammatory factors such as interleukin (IL)-β, IL-6, tumor necrosis factor (TNF)-α, and nitric oxide (NO), which incr...
Autores principales: | Chiu, Ya-Jen, Lin, Chih-Hsin, Lin, Chung-Yin, Yang, Pei-Ning, Lo, Yen-Shi, Chen, Yu-Chieh, Chen, Chiung-Mei, Wu, Yih-Ru, Yao, Ching-Fa, Chang, Kuo-Hsuan, Lee-Chen, Guey-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917106/ https://www.ncbi.nlm.nih.gov/pubmed/36768965 http://dx.doi.org/10.3390/ijms24032642 |
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