Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway

Regulatory T (Treg) cells play an important role in immune homeostasis by inhibiting cells within the innate and adaptive immune systems; therefore, the stability and immunosuppressive function of Treg cells need to be maintained. In this study, we found that the expression of insulin receptor subst...

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Detalles Bibliográficos
Autores principales: Lee, Woo Ho, Kim, Ga Eul, Hong, Kyung Jin, Kim, Hyeong Su, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917118/
https://www.ncbi.nlm.nih.gov/pubmed/36768873
http://dx.doi.org/10.3390/ijms24032551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917118/
https://www.ncbi.nlm.nih.gov/pubmed/36768873
http://dx.doi.org/10.3390/ijms24032551

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