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Insulin Receptor Substrate 1 Signaling Inhibits Foxp3 Expression and Suppressive Functions in Treg Cells through the mTORC1 Pathway
Regulatory T (Treg) cells play an important role in immune homeostasis by inhibiting cells within the innate and adaptive immune systems; therefore, the stability and immunosuppressive function of Treg cells need to be maintained. In this study, we found that the expression of insulin receptor subst...
Autores principales: | Lee, Woo Ho, Kim, Ga Eul, Hong, Kyung Jin, Kim, Hyeong Su, Lee, Gap Ryol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917118/ https://www.ncbi.nlm.nih.gov/pubmed/36768873 http://dx.doi.org/10.3390/ijms24032551 |
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