GxxxG Motif Stabilize Ion-Channel like Pores through C(α)―H···O Interaction in Aβ (1-40)

Aβ (1-40) can transfer from the aqueous phase to the bilayer and thus form stable ion-channel-like pores where the protein has alpha-helical conformation. The stability of the pores is due to the presence of the GXXXG motif. It has been reported that these ion-channel-like pores are stabilized by a...

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Detalles Bibliográficos
Autores principales: Rando, Carola, Grasso, Giuseppe, Sarkar, Dibakar, Sciacca, Michele Francesco Maria, Cucci, Lorena Maria, Cosentino, Alessia, Forte, Giuseppe, Pannuzzo, Martina, Satriano, Cristina, Bhunia, Anirban, La Rosa, Carmelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917128/
https://www.ncbi.nlm.nih.gov/pubmed/36768518
http://dx.doi.org/10.3390/ijms24032192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917128/
https://www.ncbi.nlm.nih.gov/pubmed/36768518
http://dx.doi.org/10.3390/ijms24032192

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