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GxxxG Motif Stabilize Ion-Channel like Pores through C(α)―H···O Interaction in Aβ (1-40)
Aβ (1-40) can transfer from the aqueous phase to the bilayer and thus form stable ion-channel-like pores where the protein has alpha-helical conformation. The stability of the pores is due to the presence of the GXXXG motif. It has been reported that these ion-channel-like pores are stabilized by a...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917128/ https://www.ncbi.nlm.nih.gov/pubmed/36768518 http://dx.doi.org/10.3390/ijms24032192 |