Enhanced IRE1α Phosphorylation/Oligomerization-Triggered XBP1 Splicing Contributes to Parkin-Mediated Prevention of SH-SY5Y Cell Death under Nitrosative Stress

Mutations in parkin, a neuroprotective protein, are the predominant cause of autosomal recessive juvenile Parkinson’s disease. Neuroinflammation-derived nitrosative stress has been implicated in the etiology of the chronic neurodegeneration. However, the interactions between genetic predisposition a...

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Detalles Bibliográficos
Autores principales: Chiu, Tsung-Lang, Huang, Hsin-Yi, Chang, Hui-Fen, Wu, Hsin-Rong, Wang, Mei-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917145/
https://www.ncbi.nlm.nih.gov/pubmed/36768338
http://dx.doi.org/10.3390/ijms24032017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917145/
https://www.ncbi.nlm.nih.gov/pubmed/36768338
http://dx.doi.org/10.3390/ijms24032017

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