DNA Methylation of α-Synuclein Intron 1 Is Significantly Decreased in the Frontal Cortex of Parkinson’s Individuals with GBA1 Mutations

Parkinson’s disease (PD) is a common movement disorder, estimated to affect 4% of individuals by the age of 80. Mutations in the glucocerebrosidase 1 (GBA1) gene represent the most common genetic risk factor for PD, with at least 7–10% of non-Ashkenazi PD individuals carrying a GBA1 mutation (PD-GBA...

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Detalles Bibliográficos
Autores principales: Smith, Adam R., Richards, David M., Lunnon, Katie, Schapira, Anthony H. V., Migdalska-Richards, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917152/
https://www.ncbi.nlm.nih.gov/pubmed/36769009
http://dx.doi.org/10.3390/ijms24032687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917152/
https://www.ncbi.nlm.nih.gov/pubmed/36769009
http://dx.doi.org/10.3390/ijms24032687

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