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The Cell-Specific Role of SHP2 in Regulating Bone Homeostasis and Regeneration Niches

Src homology-2 containing protein tyrosine phosphatase (SHP2), encoded by PTPN11, has been proven to participate in bone-related diseases, such as Noonan syndrome (NS), metachondromatosis and osteoarthritis. However, the mechanisms of SHP2 in bone remodeling and homeostasis maintenance are complex a...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Ye, Chengxinyue, Zhu, Yufan, Wang, Jun, Liu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917188/
https://www.ncbi.nlm.nih.gov/pubmed/36768520
http://dx.doi.org/10.3390/ijms24032202