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Moderate Constraint Facilitates Association and Force-Dependent Dissociation of HA-CD44 Complex

Binding of cell surface glycoprotein CD44 to hyaluronic acid (HA) is a key event for mediating cell adhesion, motility, metastasis, inflammatory responses and tumor development, but the regulation mechanism and its molecular basis under diverse mechanical constraints remain unclear. We herein invest...

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Detalles Bibliográficos
Autores principales: Yao, Ziyang, Wu, Jianhua, Fang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917194/
https://www.ncbi.nlm.nih.gov/pubmed/36768572
http://dx.doi.org/10.3390/ijms24032243