New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2

Very recently, we have developed a new generation of ligands targeting the cannabinoid receptor type 2 (CB2R), namely JR compounds, which combine the pharmacophoric portion of the CB2R positive allosteric modulator (PAM), EC21a, with that of the CB2R selective orthosteric agonist LV62, both synthesi...

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Detalles Bibliográficos
Autores principales: Ferrisi, Rebecca, Polini, Beatrice, Ricardi, Caterina, Gado, Francesca, Mohamed, Kawthar A., Baron, Giovanna, Faiella, Salvatore, Poli, Giulio, Rapposelli, Simona, Saccomanni, Giuseppe, Aldini, Giancarlo, Chiellini, Grazia, Laprairie, Robert B., Manera, Clementina, Ortore, Gabriella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917213/
https://www.ncbi.nlm.nih.gov/pubmed/36768458
http://dx.doi.org/10.3390/ijms24032135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917213/
https://www.ncbi.nlm.nih.gov/pubmed/36768458
http://dx.doi.org/10.3390/ijms24032135

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