Role of Histone Tails and Single Strand DNA Breaks in Nucleosomal Arrest of RNA Polymerase

Transcription through nucleosomes by RNA polymerases (RNAP) is accompanied by formation of small intranucleosomal DNA loops (i-loops). The i-loops form more efficiently in the presence of single-strand breaks or gaps in a non-template DNA strand (NT-SSBs) and induce arrest of transcribing RNAP, thus...

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Detalles Bibliográficos
Autores principales: Gerasimova, Nadezhda S., Pestov, Nikolay A., Studitsky, Vasily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917218/
https://www.ncbi.nlm.nih.gov/pubmed/36768621
http://dx.doi.org/10.3390/ijms24032295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917218/
https://www.ncbi.nlm.nih.gov/pubmed/36768621
http://dx.doi.org/10.3390/ijms24032295

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