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Addressing the Reciprocal Crosstalk between the AR and the PI3K/AKT/mTOR Signaling Pathways for Prostate Cancer Treatment

The reduction in androgen synthesis and the blockade of the androgen receptor (AR) function by chemical castration and AR signaling inhibitors represent the main treatment lines for the initial stages of prostate cancer. Unfortunately, resistance mechanisms ultimately develop due to alterations in t...

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Detalles Bibliográficos
Autores principales: Raith, Fabio, O’Donovan, Daniel H., Lemos, Clara, Politz, Oliver, Haendler, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917236/
https://www.ncbi.nlm.nih.gov/pubmed/36768610
http://dx.doi.org/10.3390/ijms24032289