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The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis

Female infertility is caused by premature ovarian failure (POF), which is triggered by the endoplasmic reticulum (ER) stress-mediated apoptosis of granulosa cells. The ER unfolded protein response (UPR(er)) is initiated to promote cell survival by alleviating excessive ER stress, but cellular apopto...

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Detalles Bibliográficos
Autores principales: Li, Huiduo, Jing, Yanan, Qu, Xiaoya, Yang, Jinyi, Pan, Pengge, Liu, Xinrui, Gao, Hui, Pei, Xiuying, Zhang, Cheng, Yang, Yanzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917250/
https://www.ncbi.nlm.nih.gov/pubmed/36769070
http://dx.doi.org/10.3390/ijms24032749