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From 2D to 3D: Development of Monolayer Dopaminergic Neuronal and Midbrain Organoid Cultures for Parkinson’s Disease Modeling and Regenerative Therapy

Parkinson’s Disease (PD) is a prevalent neurodegenerative disorder that is characterized pathologically by the loss of A9-specific dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) of the midbrain. Despite intensive research, the etiology of PD is currently unresolved, and the d...

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Detalles Bibliográficos
Autores principales: Yeap, Yee Jie, Teddy, Tng J. W., Lee, Mok Jung, Goh, Micaela, Lim, Kah Leong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917335/
https://www.ncbi.nlm.nih.gov/pubmed/36768843
http://dx.doi.org/10.3390/ijms24032523