Promotion of Protein Solubility and Reduction in Stiffness in Human Lenses by Aggrelyte-1: Implications for Reversing Presbyopia

With aging, human lenses lose the ability to focus on nearby objects due to decreases in accommodative ability, a condition known as presbyopia. An increase in stiffness or decrease in lens elasticity due to protein aggregation and insolubilization are the primary reasons for presbyopia. In this stu...

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Detalles Bibliográficos
Autores principales: Panja, Sudipta, Gaikwad, Hanmant, Rankenberg, Johanna, Nam, Mi-Hyun, Nagaraj, Ram H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917358/
https://www.ncbi.nlm.nih.gov/pubmed/36768517
http://dx.doi.org/10.3390/ijms24032196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917358/
https://www.ncbi.nlm.nih.gov/pubmed/36768517
http://dx.doi.org/10.3390/ijms24032196

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