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Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells

Gemfibrozil is a drug that has been used for over 40 years to lower triglycerides in blood. As a ligand for peroxisome proliferative-activated receptor-alpha (PPARα), which is expressed in many tissues, it induces the transcription of numerous genes for carbohydrate and lipid-metabolism. However, no...

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Detalles Bibliográficos
Autores principales: Bachmann, Cornel Manuel, Janitschke, Daniel, Lauer, Anna Andrea, Erhardt, Tobias, Hartmann, Tobias, Grimm, Marcus Otto Walter, Grimm, Heike Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917468/
https://www.ncbi.nlm.nih.gov/pubmed/36769295
http://dx.doi.org/10.3390/ijms24032972