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Both ATM and DNA-PK Are the Main Regulators of HIV-1 Post-Integrational DNA Repair

The integration of a DNA copy of an HIV-1 RNA genome into the host genome, carried out by the viral enzyme integrase, results in the formation of single-stranded gaps in cellular DNA that must be repaired. Here, we have analyzed the involvement of the PI3K kinases, ATM, ATR, and DNA-PKcs, which are...

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Detalles Bibliográficos
Autores principales: Anisenko, Andrey, Nefedova, Anastasiia, Agapkina, Yulia, Gottikh, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917498/
https://www.ncbi.nlm.nih.gov/pubmed/36769109
http://dx.doi.org/10.3390/ijms24032797