Design, Synthesis and Antimicrobial Evaluation of New N-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-2-carboxamides as Potential Inhibitors of Mycobacterial Leucyl-tRNA Synthetase

Tuberculosis remains a serious killer among infectious diseases due to its incidence, mortality, and occurrence of resistant mycobacterial strains. The challenge to discover new antimycobacterial agents forced us to prepare a series of N-(1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)(hetero)aryl-...

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Detalles Bibliográficos
Autores principales: Šlechta, Petr, Needle, Adam Anthony, Jand’ourek, Ondřej, Paterová, Pavla, Konečná, Klára, Bárta, Pavel, Kuneš, Jiří, Kubíček, Vladimír, Doležal, Martin, Kučerová-Chlupáčová, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917560/
https://www.ncbi.nlm.nih.gov/pubmed/36769275
http://dx.doi.org/10.3390/ijms24032951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917560/
https://www.ncbi.nlm.nih.gov/pubmed/36769275
http://dx.doi.org/10.3390/ijms24032951

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