STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression

STS1 and STS2, as the protein phosphatases that dephosphorylate FLT3 and cKIT, negatively regulate the self-renewal and differentiation of hematopoietic stem and progenitor cells (HSPCs). To obtain the small molecule inhibitors of STS1/STS2 phosphatase activity used to expand HSPCs both in vitro and...

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Detalles Bibliográficos
Autores principales: Li, Na, Wang, Yanhong, Wang, Anqing, Zhang, Jing, Jia, Chaoran, Yu, Chunlei, Song, Zhenbo, Wang, Shuyue, Liu, Lei, Yi, Jingwen, Bao, Yongli, Huang, Yanxin, Sun, Luguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917816/
https://www.ncbi.nlm.nih.gov/pubmed/36769312
http://dx.doi.org/10.3390/ijms24032987

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917816/
https://www.ncbi.nlm.nih.gov/pubmed/36769312
http://dx.doi.org/10.3390/ijms24032987

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