New Piperazine Derivatives of 6-Acetyl-7-hydroxy-4-methylcoumarin as 5-HT(1A) Receptor Agents

A series of 15 new derivatives of 6-acetyl-7-hydroxy-4-methylcoumarin containing a piperazine group were designed with the help of computational methods and were synthesized to study their affinity for the serotonin 5-HT(1A) and 5-HT(2A) receptors. Among them, 6-acetyl-7-{4-[4-(3-bromophenyl)piperaz...

Descripción completa

Detalles Bibliográficos
Autores principales: Ostrowska, Kinga, Leśniak, Anna, Gryczka, Weronika, Dobrzycki, Łukasz, Bujalska-Zadrożny, Magdalena, Trzaskowski, Bartosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917830/
https://www.ncbi.nlm.nih.gov/pubmed/36769117
http://dx.doi.org/10.3390/ijms24032779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917830/
https://www.ncbi.nlm.nih.gov/pubmed/36769117
http://dx.doi.org/10.3390/ijms24032779

Ejemplares similares