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Phosphorylation of Thymidylate Synthase and Dihydrofolate Reductase in Cancer Cells and the Effect of CK2α Silencing

Our previous research suggests an important regulatory role of CK2-mediated phosphorylation of enzymes involved in the thymidylate biosynthesis cycle, i.e., thymidylate synthase (TS), dihydrofolate reductase (DHFR), and serine hydroxymethyltransferase (SHMT). The aim of this study was to show whethe...

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Detalles Bibliográficos
Autores principales: Wińska, Patrycja, Sobiepanek, Anna, Pawlak, Katarzyna, Staniszewska, Monika, Cieśla, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917831/
https://www.ncbi.nlm.nih.gov/pubmed/36769342
http://dx.doi.org/10.3390/ijms24033023