Role of the Water–Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase

Fluoroquinolones are an important class of antibacterials, and rising levels of resistance threaten their clinical efficacy. Gaining a more full understanding of their mechanism of action against their target enzymes—the bacterial type II topoisomerases gyrase and topoisomerase IV—may allow us to ra...

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Detalles Bibliográficos
Autores principales: Carter, Hannah E., Wildman, Baylee, Schwanz, Heidi A., Kerns, Robert J., Aldred, Katie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917921/
https://www.ncbi.nlm.nih.gov/pubmed/36769202
http://dx.doi.org/10.3390/ijms24032879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917921/
https://www.ncbi.nlm.nih.gov/pubmed/36769202
http://dx.doi.org/10.3390/ijms24032879

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