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Role of the Water–Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase
Fluoroquinolones are an important class of antibacterials, and rising levels of resistance threaten their clinical efficacy. Gaining a more full understanding of their mechanism of action against their target enzymes—the bacterial type II topoisomerases gyrase and topoisomerase IV—may allow us to ra...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917921/ https://www.ncbi.nlm.nih.gov/pubmed/36769202 http://dx.doi.org/10.3390/ijms24032879 |