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Overexpression of the X-Linked Inhibitor of Apoptosis Protein (XIAP) in Neurons Improves Cell Survival and the Functional Outcome after Traumatic Spinal Cord Injury

Mechanical trauma to the spinal cord causes extensive neuronal death, contributing to the loss of sensory-motor and autonomic functions below the injury location. Apoptosis affects neurons after spinal cord injury (SCI) and is associated with increased caspase activity. Cleavage of X-linked inhibito...

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Detalles Bibliográficos
Autores principales: Reigada, David, Maza, Rodrigo M., Muñoz-Galdeano, Teresa, Barreda-Manso, María Asunción, Soto, Altea, Lindholm, Dan, Navarro-Ruíz, Rosa, Nieto-Díaz, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917926/
https://www.ncbi.nlm.nih.gov/pubmed/36769152
http://dx.doi.org/10.3390/ijms24032791