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The Orphan GPR50 Receptor Regulates the Aggressiveness of Breast Cancer Stem-like Cells via Targeting the NF-kB Signaling Pathway

The expression of GPR50 in CSLC and several breast cancer cell lines was assessed by RT-PCR and online platform (UALCAN, GEPIA, and R2 gene analysis). The role of GPR50 in driving CSLC, sphere formation, cell proliferation, and migration was performed using shGPR50 gene knockdown, and the role of GP...

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Detalles Bibliográficos
Autores principales: Biswas, Polash Kumar, Park, Sang Rok, An, Jongyub, Lim, Kyung Min, Dayem, Ahmed Abdal, Song, Kwonwoo, Choi, Hye Yeon, Choi, Yujin, Park, Kyoung Sik, Shin, Hyun Jin, Kim, Aram, Gil, Minchan, Saha, Subbroto Kumar, Cho, Ssang-Goo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917945/
https://www.ncbi.nlm.nih.gov/pubmed/36769125
http://dx.doi.org/10.3390/ijms24032804