Cargando…

The Orphan GPR50 Receptor Regulates the Aggressiveness of Breast Cancer Stem-like Cells via Targeting the NF-kB Signaling Pathway

The expression of GPR50 in CSLC and several breast cancer cell lines was assessed by RT-PCR and online platform (UALCAN, GEPIA, and R2 gene analysis). The role of GPR50 in driving CSLC, sphere formation, cell proliferation, and migration was performed using shGPR50 gene knockdown, and the role of GP...

Descripción completa

Detalles Bibliográficos
Autores principales:	Biswas, Polash Kumar, Park, Sang Rok, An, Jongyub, Lim, Kyung Min, Dayem, Ahmed Abdal, Song, Kwonwoo, Choi, Hye Yeon, Choi, Yujin, Park, Kyoung Sik, Shin, Hyun Jin, Kim, Aram, Gil, Minchan, Saha, Subbroto Kumar, Cho, Ssang-Goo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9917945/ https://www.ncbi.nlm.nih.gov/pubmed/36769125 http://dx.doi.org/10.3390/ijms24032804

Ejemplares similares

GPR50 Promotes Hepatocellular Carcinoma Progression via the Notch Signaling Pathway through Direct Interaction with ADAM17
por: Saha, Subbroto Kumar, et al.
Publicado: (2020)

High Expression of TTYH3 Is Related to Poor Clinical Outcomes in Human Gastric Cancer
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Multi-Omics Analysis of SOX4, SOX11, and SOX12 Expression and the Associated Pathways in Human Cancers
por: Seok, Jaekwon, et al.
Publicado: (2021)

Improved Wound Healing and Skin Regeneration Ability of 3,2′-Dihydroxyflavone-Treated Mesenchymal Stem Cell-Derived Extracellular Vesicles
por: Kim, Sehee, et al.
Publicado: (2023)

New therapeutic approach with extracellular vesicles from stem cells for interstitial cystitis/bladder pain syndrome
por: Dayem, Ahmed Abdal, et al.
Publicado: (2022)

High Therapeutic and Esthetic Properties of Extracellular Vesicles Produced from the Stem Cells and Their Spheroids Cultured from Ocular Surgery-Derived Waste Orbicularis Oculi Muscle Tissues
por: Lim, Kyung Min, et al.
Publicado: (2021)

TTYH3 Modulates Bladder Cancer Proliferation and Metastasis via FGFR1/H-Ras/A-Raf/MEK/ERK Pathway
por: Biswas, Polash Kumar, et al.
Publicado: (2022)

Advanced 3D dynamic culture system with transforming growth factor-β3 enhances production of potent extracellular vesicles with modified protein cargoes via upregulation of TGF-β signaling
por: Min Lim, Kyung, et al.
Publicado: (2022)

The Anti-Cancer Effect of Polyphenols against Breast Cancer and Cancer Stem Cells: Molecular Mechanisms
por: Abdal Dayem, Ahmed, et al.
Publicado: (2016)

Valproic Acid Induces Endocytosis-Mediated Doxorubicin Internalization and Shows Synergistic Cytotoxic Effects in Hepatocellular Carcinoma Cells
por: Saha, Subbroto Kumar, et al.
Publicado: (2017)

Recent Advances in Disease Modeling and Drug Discovery for Diabetes Mellitus Using Induced Pluripotent Stem Cells
por: Kawser Hossain, Mohammed, et al.
Publicado: (2016)

Improved Isolation and Culture of Urine-Derived Stem Cells (USCs) and Enhanced Production of Immune Cells from the USC-Derived Induced Pluripotent Stem Cells
por: Kim, Kyeongseok, et al.
Publicado: (2020)

Prognostic role of EGR1 in breast cancer: a systematic review
por: Saha, Subbroto Kumar, et al.
Publicado: (2021)

Correlation between Oxidative Stress, Nutrition, and Cancer Initiation
por: Saha, Subbroto Kumar, et al.
Publicado: (2017)

The Role of Reactive Oxygen Species (ROS) in the Biological Activities of Metallic Nanoparticles
por: Abdal Dayem, Ahmed, et al.
Publicado: (2017)

Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells
por: Hossain, Mohammed Kawser, et al.
Publicado: (2018)

Rapid production method with increased yield of high‐purity extracellular vesicles obtained using extended mitochondrial targeting domain peptide
por: Lim, Kyung Min, et al.
Publicado: (2022)

Molecular Mechanisms of the Anti-Obesity and Anti-Diabetic Properties of Flavonoids
por: Kawser Hossain, Mohammed, et al.
Publicado: (2016)

Modulation of Osteogenic Differentiation of Adipose-Derived Stromal Cells by Co-Treatment with 3, 4’-Dihydroxyflavone, U0126, and N-Acetyl Cysteine
por: Song, Kwonwoo, et al.
Publicado: (2022)

Systematic Multiomics Analysis of Alterations in C1QBP mRNA Expression and Relevance for Clinical Outcomes in Cancers
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Expression of ATP/GTP Binding Protein 1 Has Prognostic Value for the Clinical Outcomes in Non-Small Cell Lung Carcinoma
por: Kwak, Hee Jeong, et al.
Publicado: (2020)

Application of Adult and Pluripotent Stem Cells in Interstitial Cystitis/Bladder Pain Syndrome Therapy: Methods and Perspectives
por: Abdal Dayem, Ahmed, et al.
Publicado: (2020)

Role of Oxidative Stress in Stem, Cancer, and Cancer Stem Cells
por: Dayem, Ahmed Abdal, et al.
Publicado: (2010)

Antiviral Effect of Methylated Flavonol Isorhamnetin against Influenza
por: Dayem, Ahmed Abdal, et al.
Publicado: (2015)

Silver Nanoparticles: Two-Faced Neuronal Differentiation-Inducing Material in Neuroblastoma (SH-SY5Y) Cells
por: Abdal Dayem, Ahmed, et al.
Publicado: (2018)

Sestrin2 Expression Has Regulatory Properties and Prognostic Value in Lung Cancer
por: Chae, Hee Sung, et al.
Publicado: (2020)

The Impact of Metallic Nanoparticles on Stem Cell Proliferation and Differentiation
por: Abdal Dayem, Ahmed, et al.
Publicado: (2018)

Hydrodynamic shear stress promotes epithelial-mesenchymal transition by downregulating ERK and GSK3β activities
por: Choi, Hye Yeon, et al.
Publicado: (2019)

Cytokeratin 19 (KRT19) has a Role in the Reprogramming of Cancer Stem Cell-Like Cells to Less Aggressive and More Drug-Sensitive Cells
por: Saha, Subbroto Kumar, et al.
Publicado: (2018)

Thermostable Human Basic Fibroblast Growth Factor (TS-bFGF) Engineered with a Disulfide Bond Demonstrates Superior Culture Outcomes in Human Pluripotent Stem Cell
por: Kim, Sejong, et al.
Publicado: (2023)

3,2′-Dihydroxyflavone Improves the Proliferation and Survival of Human Pluripotent Stem Cells and Their Differentiation into Hematopoietic Progenitor Cells
por: Kim, Kyeongseok, et al.
Publicado: (2020)

The therapeutic potential of orphan GPCRs, GPR35 and GPR55
por: Shore, Derek M., et al.
Publicado: (2015)

Systematic expression alteration analysis of master reprogramming factor OCT4 and its three pseudogenes in human cancer and their prognostic outcomes
por: Saha, Subbroto Kumar, et al.
Publicado: (2018)

Alterations and Co-Occurrence of C-MYC, N-MYC, and L-MYC Expression are Related to Clinical Outcomes in Various Cancers
por: Lee, Moonjung, et al.
Publicado: (2023)

Effects of carrier solutions on the viability and efficacy of canine adipose-derived mesenchymal stem cells
por: Sultana, Tania, et al.
Publicado: (2022)

Opposing Regulation of Cancer Properties via KRT19-Mediated Differential Modulation of Wnt/β-Catenin/Notch Signaling in Breast and Colon Cancers
por: Saha, Subbroto Kumar, et al.
Publicado: (2019)

Generation of pancreatic β cells for treatment of diabetes: advances and challenges
por: Shahjalal, Hussain Md., et al.
Publicado: (2018)

Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3‐L1 preadipocytes
por: Yao, Zhenyu, et al.
Publicado: (2022)

The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development
por: Wojciech, Stefanie, et al.
Publicado: (2018)

Recent advances in organoid culture for insulin production and diabetes therapy: methods and challenges
por: Dayem, Ahmed Abdal, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2i00ttu3ev4f8a2e2f34g9dn26