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Physical and Functional Characterization of PLGA Nanoparticles Containing the Antimicrobial Peptide SAAP-148

Synthetic antimicrobial and antibiofilm peptide (SAAP-148) commits significant antimicrobial activities against antimicrobial resistant (AMR) planktonic bacteria and biofilms. However, SAAP-148 is limited by its low selectivity index, i.e., ratio between cytotoxicity and antimicrobial activity, as w...

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Detalles Bibliográficos
Autores principales: Ali, Muhanad, van Gent, Miriam E., de Waal, Amy M., van Doodewaerd, Bjorn R., Bos, Erik, Koning, Roman I., Cordfunke, Robert A., Drijfhout, Jan Wouter, Nibbering, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918011/
https://www.ncbi.nlm.nih.gov/pubmed/36769188
http://dx.doi.org/10.3390/ijms24032867