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Tet-Regulated Expression and Optical Clearing for In Vivo Visualization of Genetically Encoded Chimeric dCas9/Fluorescent Protein Probes

The catalytically inactive mutant of Cas9 (dCas9) endonuclease has multiple biomedical applications, with the most useful being the activation/repression of transcription. dCas9 family members are also emerging as potential experimental tools for gene mapping at the level of individual live cells an...

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Detalles Bibliográficos
Autores principales: Maloshenok, Liliya, Abushinova, Gerel, Kazachkina, Natalia, Bogdanov, Alexei, Zherdeva, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918104/
https://www.ncbi.nlm.nih.gov/pubmed/36769948
http://dx.doi.org/10.3390/ma16030940