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Vaccines for prion diseases: a realistic goal?

Prion diseases are fatal infectious neurodegenerative disorders and prototypic conformational diseases, caused by the conformational conversion of the normal cellular prion protein (PrP(C)) into the pathological PrP(Sc) isoform. Examples are scrapie in sheep and goat, bovine spongiform encephalopath...

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Detalles Bibliográficos
Autores principales: Napper, Scott, Schatzl, Hermann M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918406/
https://www.ncbi.nlm.nih.gov/pubmed/36764940
http://dx.doi.org/10.1007/s00441-023-03749-7