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Oxygen transfer reaction of haloalkyl amides catalyzed by phenylboronic acid
Nitrile derivatives are important building blocks in organic synthesis. Herein, we report the serendipitous discovery of an oxygen transfer reaction that produces hydroxyalkyl nitriles from the sequential dehydration and hydrolysis of haloalkyl amides. Product yields of up to 91% were achieved, and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918490/ https://www.ncbi.nlm.nih.gov/pubmed/36765132 http://dx.doi.org/10.1038/s42004-023-00824-6 |