TRAF4-mediated ubiquitination-dependent activation of JNK/Bcl-xL drives radioresistance

The E3 ligase TNF receptor-associated factor 4 (TRAF4) is upregulated and closely associated with tumorigenesis and the progression of multiple human malignancies. However, its effect on radiosensitivity in colorectal cancer (CRC) has not been elucidated. The present study found that TRAF4 was signi...

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Detalles Bibliográficos
Autores principales: Dong, Xin, Li, Xiaoying, Gan, Yu, Ding, Jie, Wei, Baojun, Zhou, Li, Cui, Wei, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918491/
https://www.ncbi.nlm.nih.gov/pubmed/36765039
http://dx.doi.org/10.1038/s41419-023-05637-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918491/
https://www.ncbi.nlm.nih.gov/pubmed/36765039
http://dx.doi.org/10.1038/s41419-023-05637-y

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