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TRAF4-mediated ubiquitination-dependent activation of JNK/Bcl-xL drives radioresistance
The E3 ligase TNF receptor-associated factor 4 (TRAF4) is upregulated and closely associated with tumorigenesis and the progression of multiple human malignancies. However, its effect on radiosensitivity in colorectal cancer (CRC) has not been elucidated. The present study found that TRAF4 was signi...
Autores principales: | Dong, Xin, Li, Xiaoying, Gan, Yu, Ding, Jie, Wei, Baojun, Zhou, Li, Cui, Wei, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918491/ https://www.ncbi.nlm.nih.gov/pubmed/36765039 http://dx.doi.org/10.1038/s41419-023-05637-y |
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