Structural insights into pathogenic mechanism of hypohidrotic ectodermal dysplasia caused by ectodysplasin A variants

EDA is a tumor necrosis factor (TNF) family member, which functions together with its cognate receptor EDAR during ectodermal organ development. Mutations of EDA have long been known to cause X‐linked hypohidrotic dysplasia in humans characterized by primary defects in teeth, hair and sweat glands....

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Detalles Bibliográficos
Autores principales: Yu, Kang, Huang, Chenhui, Wan, Futang, Jiang, Cailing, Chen, Juan, Li, Xiuping, Wang, Feng, Wu, Jian, Lei, Ming, Wu, Yiqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918506/
https://www.ncbi.nlm.nih.gov/pubmed/36765055
http://dx.doi.org/10.1038/s41467-023-36367-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918506/
https://www.ncbi.nlm.nih.gov/pubmed/36765055
http://dx.doi.org/10.1038/s41467-023-36367-6

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