Hedgehog is relayed through dynamic heparan sulfate interactions to shape its gradient

Cellular differentiation is directly determined by concentration gradients of morphogens. As a central model for gradient formation during development, Hedgehog (Hh) morphogens spread away from their source to direct growth and pattern formation in Drosophila wing and eye discs. What is not known is...

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Detalles Bibliográficos
Autores principales: Gude, Fabian, Froese, Jurij, Manikowski, Dominique, Di Iorio, Daniele, Grad, Jean-Noël, Wegner, Seraphine, Hoffmann, Daniel, Kennedy, Melissa, Richter, Ralf P., Steffes, Georg, Grobe, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918555/
https://www.ncbi.nlm.nih.gov/pubmed/36765094
http://dx.doi.org/10.1038/s41467-023-36450-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918555/
https://www.ncbi.nlm.nih.gov/pubmed/36765094
http://dx.doi.org/10.1038/s41467-023-36450-y

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