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Hedgehog is relayed through dynamic heparan sulfate interactions to shape its gradient
Cellular differentiation is directly determined by concentration gradients of morphogens. As a central model for gradient formation during development, Hedgehog (Hh) morphogens spread away from their source to direct growth and pattern formation in Drosophila wing and eye discs. What is not known is...
Autores principales: | Gude, Fabian, Froese, Jurij, Manikowski, Dominique, Di Iorio, Daniele, Grad, Jean-Noël, Wegner, Seraphine, Hoffmann, Daniel, Kennedy, Melissa, Richter, Ralf P., Steffes, Georg, Grobe, Kay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918555/ https://www.ncbi.nlm.nih.gov/pubmed/36765094 http://dx.doi.org/10.1038/s41467-023-36450-y |
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