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H2B ubiquitination recruits FACT to maintain a stable altered nucleosome state for transcriptional activation

Histone H2B mono-ubiquitination at lysine 120 (ubH2B) has been found to regulate transcriptional elongation by collaborating with the histone chaperone FACT (Facilitates Chromatin Transcription) and plays essential roles in chromatin-based transcriptional processes. However, the mechanism of how ubH...

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Detalles Bibliográficos
Autores principales: Luo, Anfeng, Kong, Jingwei, Chen, Jun, Xiao, Xue, Lan, Jie, Li, Xiaorong, Liu, Cuifang, Wang, Peng-Ye, Li, Guohong, Li, Wei, Chen, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918737/
https://www.ncbi.nlm.nih.gov/pubmed/36765085
http://dx.doi.org/10.1038/s41467-023-36467-3