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Glycerol based carbon sulfonic acid catalyzed synthesis, in silico studies and in vitro biological evaluation of isonicotinohydrazide derivatives as potent antimicrobial and anti-tubercular agents

The present pathway involves synthesis of isonicotinohydrazide derivatives using isoniazid and diversely substituted aldehydes in the presence of EtOH and catalytic amount of glycerol based carbon sulfonic acid catalyst. The developed pathway has so many merits like excellent yields (91–98%), short...

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Detalles Bibliográficos
Autores principales: Sethiya, Ayushi, Joshi, Deepkumar, Manhas, Anu, Sahiba, Nusrat, Agarwal, Dinesh K., Jha, Prakash C., Agarwal, Shikha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918772/
https://www.ncbi.nlm.nih.gov/pubmed/36785822
http://dx.doi.org/10.1016/j.heliyon.2023.e13226