In vitro expansion of Wilms’ tumor protein 1 epitope-specific primary T cells from healthy human peripheral blood mononuclear cells

Wilms’ tumor protein 1 (WT1) is a tumor-associated antigen overexpressed in various cancers. As a self-antigen, negative selection reduces the number of WT1-specific T cell receptors (TCRs). Here, we provide a protocol to generate WT1(37-45)-specific TCRs using healthy human peripheral blood mononuc...

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Detalles Bibliográficos
Autores principales: van der Heijden, Sanne, Flumens, Donovan, Versteven, Maarten, Peeters, Stefanie, Reu, Hans De, Campillo-Davo, Diana, Willemen, Yannick, Ogunjimi, Benson, Van Tendeloo, Viggo, Berneman, Zwi N., Anguille, Sébastien, Smits, Evelien, Lion, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918782/
https://www.ncbi.nlm.nih.gov/pubmed/36853720
http://dx.doi.org/10.1016/j.xpro.2023.102053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918782/
https://www.ncbi.nlm.nih.gov/pubmed/36853720
http://dx.doi.org/10.1016/j.xpro.2023.102053

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