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Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model
OBJECTIVE: Renal fibrosis is a hallmark for chronic kidney disease (CKD), and often leads to end stage renal disease (ESRD). However, limited interventions are available clinically to ameliorate or reverse renal fibrosis. METHODS: Herein, we evaluated whether blockade of endotrophin through neutrali...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918787/ https://www.ncbi.nlm.nih.gov/pubmed/36696925 http://dx.doi.org/10.1016/j.molmet.2023.101680 |