Endotrophin neutralization through targeted antibody treatment protects from renal fibrosis in a podocyte ablation model

OBJECTIVE: Renal fibrosis is a hallmark for chronic kidney disease (CKD), and often leads to end stage renal disease (ESRD). However, limited interventions are available clinically to ameliorate or reverse renal fibrosis. METHODS: Herein, we evaluated whether blockade of endotrophin through neutrali...

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Detalles Bibliográficos
Autores principales: An, Yu A., Xiong, Wei, Chen, Shiuhwei, Bu, Dawei, Rutkowski, Joseph M., Berger, Joel P., Kusminski, Christine M., Zhang, Ningyan, An, Zhiqiang, Scherer, Philipp E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918787/
https://www.ncbi.nlm.nih.gov/pubmed/36696925
http://dx.doi.org/10.1016/j.molmet.2023.101680

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