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Immunofluorescence assay for demyelination, remyelination, and proliferation in an acute cuprizone mouse model

Here, we present a protocol to assess demyelination in the corpus callosum of an acute cuprizone mouse model, which is routinely used to induce demyelination for studying myelin regeneration in the rodent brain. We describe the tracing of neural stem cells via intraperitoneal injection of tamoxifen...

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Detalles Bibliográficos
Autores principales: Clawson, Elizabeth D., Radecki, Daniel Z., Samanta, Jayshree
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918794/
https://www.ncbi.nlm.nih.gov/pubmed/36853716
http://dx.doi.org/10.1016/j.xpro.2023.102072